Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Azilect (rasagiline). 21/06/ Azilect – EMEA/H/C/ – IA//G. List item. Azilect: EPAR – Product Information (PDF/ KB) of the marketing authorisation; Annex IIIA – Labelling; Annex IIIB – Package leaflet. PACKAGE LEAFLET: INFORMATION FOR THE USER. AZILECT 1 mg tablets. Rasagiline. Read all of this leaflet carefully before you start.
Do not drive and do not use tools or machines until the dizziness has passed.
Rasagiline for Parkinson’s disease (Azilect) | Patient
Dosage adjustment for mild impairment; do not use in moderate or severe impairment. Rasagiline at the recommended therapeutic dose was also shown to be a potent and irreversible inhibitor of MAO-B in platelets. Where can I find Teva medications? Do not drive and do not use tools or machines until the dizziness has passed Muscle weakness, balance problems, falls If this becomes troublesome, let your doctor indert Constipation Eat a well-balanced diet and drink plenty of water each day Dry mouth Try chewing sugar-free gum or sucking sugar-free sweets Chest pains, skin problems Let your doctor know about this straightaway Flu-like symptoms, feeling unwell, aches and pains, loss of appetite, feeling depressed, increased urgency to pass urine, conjunctivitis, unusual dreams and thoughts Let your doctor know if any of these become troublesome.
The results of a clinical trial designed to examine the effects of the drug on blood pressure when it is administered with increasing doses of tyramine indicates the functional selectivity can be incomplete when healthy subjects ingest large amounts of tyramine while receiving recommended doses of rasagiline. Inform patients that they should contact their healthcare provider if they take ciprofloxacin aailect a similar drug that could increase blood levels of rasagiline.
Support respiration; monitor body temperature; intensive zzilect of hyperpyrexia may be required; maintenance of fluid and electrolyte balance is essential. In this article arrow-down About rasagiline for Parkinson’s disease arrow-down Before taking rasagiline for Parkinson’s disease arrow-down How to take rasagiline arrow-down Getting the most from your treatment arrow-down Can rasagiline cause problems?
The metabolism of rasagiline proceeds through two main pathways: If a doss is missed, the patient should not double the dose. Take one tablet each day. Taking rasagiline helps to prevent this problem. In the study where Azilect was used alone, patients taking 1 mg of the medicine once a day had an average fall in UPDRS score of 0.
Multiple doses of rasagiline of 0. No additional in vivo trials have investigated the effect of rasagiline on other drugs metabolized by the cytochrome P enzyme system. It blocks the enzyme monoamine oxidase type B, which breaks down the neurotransmitter dopamine in the brain.
The pharmacokinetic profile of rasagiline is similar in men and women. When inxert dose of levodopa starts to wear off, the symptoms of Parkinson’s disease can return.
Azlect you find this information useful? More detail is available in the summary of product characteristics. There should be at least 14 days between stopping treatment with Azilect and starting treatment with another monoamine-oxidase inhibitor or with pethidine.
This is known as an ‘end-of-dose fluctuation’. If you have any questions about this medicine ask your pharmacist. May cause hypertension including severe hypertensive syndromes at recommended doses May cause serotonin syndrome when used with antidepressants May cause falling asleep during activities of daily living, daytime drowsiness, and somnolence May cause hypotension, especially orthostatic May cause or exacerbate dyskinesia.
John’s Wort, cyclobenzaprine or another selective or non-selective MAO inhibitor. Rasagiline increases the amount of dopamine in the brain and so helps to relieve these symptoms. The catalog displays all strengths and sizes along with the description, imprint code, NDC and photo for each product. They should contact their healthcare provider before taking analgesics.
The most common side effect with Azilect seen in more than 1 patient in packsge is headache. Effect of Other Drugs on the Metabolism of rasagiline: If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist. Further reading and references.
MAO-B is the major form in the human brain. Azilect was more effective than placebo in all of the studies.
Join the discussion on the forums. How to store rasagiline Important information about all medicines. These symptoms may occur more frequently during initial therapy or with an increase in dose at any time. Meperidine – risk of serotonin syndrome Dextromethorphan – risk of psychosis or bizarre behavior MAO inhibitors – risk of non-selective MAO inhibition and hypertensive crisis.
Azilect must not be used in patients who have severe problems with their liver. Inform patients that hallucinations or other manifestations of psychotic-like behavior can occur when taking rasagiline. Contact their healthcare provider if elevation of blood pressure occurs.
Advise patients about the potential for sedating effects associated with rasagiline, including somnolence and particularly to the possibility of falling asleep while engaged in activities of daily living.
If the pharmacy doesn’t regularly stock a certain medication from Teva, ask if it can be ordered for you at no additional cost.
As your condition improves and your body movements become easier, be careful not to overdo physical activities. Product details Name Azilect.
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